The expression of viral vectors in HEK 293 cells is a widely used procedure to obtain sufficient quantities of the desired virus. The manufacturing and purification process of these products leaves
Improvement of in situ Follicular Activation and Early Development in Cryopreserved Human Ovarian Cortical Tissue by Co-Culturing with Mesenchymal Stem Cells.
Follicle losses and network degeneration are major challenges in the ovarian tissue culture system. Mesenchymal (MSC) stem cells emit the cocktail of growth and cytokines that support adjacent cells
N-acetyltransferase 2 acetylator genotype-dependent N-acetylation of 4-aminobiphenyl in cryopreserved human hepatocytes.
Arylamine N-Acetyltransferase is an xenobiotic metabolic enzyme responsible for detoxification of many drugs and carcinogens. Two n-acetyltransferase proteins (NAT1 and NAT2) are expressed in humans
The level of disbursement of iliaca artery of the human kriopreserved allografts (CHIAA) directly affects the fatigue of structural changes that occur during this process.
Experiments were carried out at ten Chiaa. 10% dimethylsulphoxide in hydroxyethyl 6% starch solution is used as cryoprotectant; All Chiaa is cooled at a level controlled and stored in the liquid
Variations between individuals and inter-regions in the activity of enteric drug metabolism Activities: Results with the Human Intestinal Mucosa epithelium CryoPreserved (Chim) from the small intestine of 14 donors
We have previously reported successful insulation and cryopreservation of human intestinal mucosa (CHIM) with the viability retention and activity of drug metabolism enzymes. Here we report the
Cryopreserved human oocytes and cord blood cells can produce macar stem cells somatic blood cells parent cells with hla homozygous type
Human pluripotent stem cells (PSC) through somatic cell nuclear transfer (SCNT) may be an important source for regenerative treatment. Low derivation efficiency of stem cells and human oocyte
The purpose of our study is to assess the impact of different disbursement protocols in morphological changes that arise in the grafting of cryopreserved human saphenous veins. This study was
MiR-1193 represses the proliferation and induces the apoptosis of interleukin-1β-treated fibroblast-like synoviocytes via targeting JAK3
Objective: To explore the role of miR-1193 / Janus kinase 3 (JAK3) axis and the potential mechanisms in rheumatoid arthritis (RA).Methods: The dysregulated genes and microRNAs (miRNAs) are filtered
Sonic Hedgehog Regulates Proliferation, Migration and Invasion of Synoviocytes in Rheumatoid Arthritis via JNK Signaling
Enabled fibroblast-like synoviocytes (FLSs) plays a central role in synovial pannus formation and joint destruction in rheumatoid arthritis (RA). FLSs targeting could be a potential therapeutic
MicroRNA-495 attenuates proliferation and inflammatory response in rheumatoid arthritis fibroblast-like synoviocytes through attenuating β-catenin pathway
Fibroblast like synoviocytes (FLSs) exert important effects in the occurrence and progression of rheumatoid arthritis (RA). MicroRNA-495 (miR-495) can regulate growth behavior of many cell types.