At-408 And Medchemexpress

Lab Reagents

Human IgG antibody Laboratories manufactures the at-408 and medchemexpress reagents distributed by Genprice. The At-408 And Medchemexpress reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact MedChemExpress Inc.. Other At-408 products are available in stock. Specificity: At-408 Category: And Group: Medchemexpress

Medchemexpress information

p53 and MDM2 proteins-interaction-inhibitor (chiral)

HY-70027 10mM/1mL
EUR 1254

p53 and MDM2 proteins-interaction-inhibitor (dihydrochloride)

HY-70027A 100mg
EUR 4138.8

p53 and MDM2 proteins-interaction-inhibitor (racemic)

HY-70028 100mg
EUR 2606.4


ELA-E0359r 96 Tests
EUR 1063.2

SARS-CoV-2 (COVID-19) NSP10 Recombinant Protein

10-408 0.1 mg
EUR 651.3
Description: Nsp10 have shown that it is a 15-kDa protein of unknown function that has been shown to interact with itself, nsp1, and nsp7. It colocalizes with N to sites of viral replication and is essential for replication. It plays a pivotal role in viral transcription by stimulating both nsp14 3'-5' exoribonuclease and nsp16 2'-O-methyltransferase activities. Therefore plays an essential role in viral mRNAs cap methylation. Nsp10 is a critical regulator of coronavirus RNA synthesis and may play an important role in polyprotein processing.

DNase I (MBG)

408-050 50 mg
EUR 86.4

DNase I (MBG)

408-1000 1000 mg
EUR 699.6

DNase I (MBG)

408-250 250 mg
EUR 247.2

ICOS / CD278 (C136S, C137S) Recombinant Protein

11-408 0.1 mg
EUR 714.3
Description: Inducible T-cell costimulator (ICOS) is also known as Activation-inducible lymphocyte immunomediatory molecule (AILIM), CD278, which belongs to the CD28 family of immune costimulatory receptors consisting of CD28, CTLA-4 and PD-1. ICOS enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. CD278 / ICOS prevents the apoptosis of pre-activated T-cells and also plays a critical role in CD40-mediated class switching of immunoglobin isotypes.

CD134 [OX40] Recombinant Protein

90-408 25 ug
EUR 588.3
Description: CD134 (OX40) is a T cell activation antigen structurally belonging to a lymphocyte-specific subgroup of the nerve growth factor and tumor necrosis factor receptor superfamily, which also includes the T cell antigen CD27, B cell antigen CD40, FAS antigen and the T cell activation antigen 4-1BB. The human CD134 protein is expressed only on activated CD4+ T blasts, and its ligand has been identified as gp34. Interactions between CD134 and its ligand in vivo are necessary for the differentiation of activated B cells into highly immunoglobulin-producing cells, however not involved in other pathways of antigen-driven differentiation of B cells such as development of memory cells in the germinal centers. In addition, the CD134 and gp34 system directly mediate adhesion of activated T cells to vascular endothelial cells, and contribute to growth stimulation of the virus-infected T cells.

Chitinase-3-Like Protein 1 Recombinant Protein

91-408 0.05 mg
EUR 556.8
Description: Chitinase-3-Like Protein 1 (CHI3L1) belongs to the glycosyl hydrolase 18 family. CHI3L1 is expressed in activated macrophages, articular chondrocytes, synovial cells as well as in liver. It lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. CHI3L1 is thought to play a role in defense against pathogens, or in tissue remodeling, and in the capacity of cells to respond to and cope with changes in their environment. In addition, CHI3L1 is associated with susceptibility to asthma-related traits type 7 (ASRT7) which assessed by methacholine challenge test, serum IgE levels, atopy, and atopic dermatitis.

Nectin-2 Recombinant Protein

92-408 0.05 mg
EUR 437.1
Description: Nectin-2( CD112) is a member of the nectin family, which contains two Ig-like C2-type domains and one Ig-like V-type domain in the extracellular region. Nectins are type I transmembrane glycoproteins that are calcium-independent immunoglobulin (Ig)-like cell adhesion molecules (CAMs). Nectin2 is widely expressed in human tissues including brain, spinal cord, spleen, kidney, heart and liver. It can form trans-heterodimers with PVRL3/nectin-3 and interacts with CD226. Mutations of alleles of the murine CD112 gene can result in conditions such as morphologically aberrant spermatozoa. It may function in allergic reactions, and accordingly may used as a novel target for anti-allergic therapy.

IFNAR 2 Recombinant Protein

96-408 1 mg
EUR 2793.3
Description: Interferon alpha/beta receptor 2 (IFNAR2) is also known as IFN-alpha binding protein, IFN-alpha/beta receptor 2, Type I interferon receptor 2, IFNABR and IFNARB, which is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. IFNAR2 can associate with IFNAR1 to form the type I interferon receptor. IFNAR2 is a receptor for interferons alpha and beta.IFNAR2 involves in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 of IFNAR2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 of IFNAR2 is a potent inhibitor of type I IFN receptor activity.Genetic variations in IFNAR2 influence susceptibility to hepatitis B virus (HBV) infection.

Ral Activation Assay

STA-408 20 assays
EUR 908.4
Description: Our Ral Activation Assay uses visible agarose beads to selectively precipitate the active form of Ral protein. The precipitated small GTPase is then detected by Western blot using a Ral-specific antibody included in the kit.

CRE-2A-GFP (CMV-Neo), Ultra titer lentivirus

ULVP-408 1 x109 IFU/ml x 50 ul
EUR 1278
Description: Pre-made lentiviral particles bicistronically express individual nuclear permeable CRE recombinase and the GFP marker under the same suCMV promoter. A Neomycin marker was expressed under RSV promoter. Virus concentrated and buffer changed into PBS solution.

Recombinant (E.Coli, His-tag) Human Secreted Phospholipase A2-IID

RP-408 10 ug
EUR 343.2


A3196-10 10 mg
EUR 205.2
Description: AT101, a natural product from cottonseed with a BH3-mimetic structure, was identified as a small molecule inhibitor of Bcl-2/Bcl-xL/Mcl-1 that potently induces apoptosis in various cancer cell lines [1].