Lnc RNA ZFAS1 regulates the proliferation, apoptosis, inflammatory response and autophagy of fibroblast-like synoviocytes via miR-2682-5p/ADAMTS9 axis in Rheumatoid Arthritis

Background: Rheumatoid arthritis (RA) is an autoimmune disease often. Emerging evidence suggests that antisense ZNFX1 RNA1 (ZFAS1) participate in physiological and pathological processes in RA. However, knowledge ZFAS1 in RA is limited, the potential paths ZFAS1 work needs to be investigated further.


Methods: Levels ZFAS1, microRNA (mir) -2682-5p, and ADAM metallopeptidase with thrombospondin type 1 motif 9 (ADAMTS9) were estimated using real-time quantitative polymerase chain reaction (qRT-PCR) assay. 3- (4,5-dimethylthiazol-2-yl) -2,5-diphenyltetrazolium bromide (MTT) assay was performed to explore the capabilities of cell proliferation in fibroblast-like synoviocytes (FLS-RA). Cell apoptosis was measured by flow cytometry. Also, the rate ADAMTS9, a protein associated with apoptosis, Cleaved-caspase-3 (active large subunit), and autophagy-related protein identified adopt western blot. Enzyme-linked immunosorbent assay (ELISA) was conducted to determine the production of inflammatory cytokines. In addition, the relationship between miR-2682-5p and ZFAS1 or ADAMTS9 verified utilize dual-luciferase reporter assay.


Results: High levels of ZFAS1 and ADAMTS9, and low levels of miR-2682-5p were observed in RA synovial tissue and FLS-RA. Knockdown of ZFAS1 cause a reduction of cell proliferation, inflammation, autophagy, and increased apoptosis in RA-FLS, while this effect was abolished by getting back in the inhibition of miR-2682-5p. In addition, miR-2682-5p effect on the phenotype of cells and the inflammatory response was eliminated by ADAMTS9 upregulation in RA-FLS. Mechanically, ZFAS1 given its role through miR-2682-5p / ADAMTS9 axis in RA.


Conclusion: ZFAS1 / miR-2682-5p / ADAMTS9 axis can modulate the behavior of cells, the inflammatory response in RA-FLS, may provide potential therapeutic targets for the treatment of RA.
Keywords: Rheumatoid arthritis; cell autophagy; inflammatory.

Lnc RNA ZFAS1 regulates the proliferation, apoptosis, inflammatory response and autophagy of fibroblast-like synoviocytes via miR-2682-5p/ADAMTS9 axis in Rheumatoid Arthritis
Lnc RNA ZFAS1 regulates the proliferation, apoptosis, inflammatory response and autophagy of fibroblast-like synoviocytes via miR-2682-5p/ADAMTS9 axis in Rheumatoid Arthritis

Estrogen downregulates the expression of TAK1 in human fibroblast-like synoviocytes and models of rheumatoid arthritis

Transforming growth factor-β-activated kinase 1 (TAK1), a member of the protein kinase family of mitogen-activated, plays a key role in the pathogenesis and progression of rheumatoid arthritis (RA). Estrogen has been reported previously to delay the progression of arthritis. However, the exact association between TAK1 and estrogen remains elusive. This study demonstrated that TAK1 synoviocytes is upregulated in patients with RA compared to patients with osteoarthritis and healthy controls. In addition, the TAK1 also expressed in cultured fibroblast-like synoviocytes (FLS), and the levels were decreased significantly in 17β-estradiol (E2) -treated cells in a dose-dependent manner

. In addition, administration of E2 significantly decreased expression of TAK1 and attenuated the development of collagen-induced arthritis (CIA). Taken together, the findings from this study suggest that E2 mediates TAK1 decline in both FLS and the CIA, which later resulted in the suppression of pathological processes CIA. Therefore, estrogen may serve as a potential therapeutic agent for the treatment of RA by targeting TAK1.

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Human E3 ubiquitin- protein ligase synoviolin, SYVN1 ELISA KIT
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Human E3 ubiquitin-protein ligase synoviolin (SYVN1) ELISA Kit
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ELISA kit for Human E3 ubiquitin-protein ligase synoviolin (SYVN1)
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Description: Quantitative sandwich ELISA for measuring Human E3 ubiquitin-protein ligase synoviolin (SYVN1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

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Synovial Apoptosis Inhibitor 1, Synoviolin Antibody
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E3 Ubiquitin-Protein Ligase Synoviolin (HRD1) Antibody
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E3 Ubiquitin-Protein Ligase Synoviolin (HRD1) Antibody
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Mouse E3 ubiquitin- protein ligase synoviolin, Syvn1 ELISA KIT
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E3 Ubiquitin-Protein Ligase Synoviolin (SYVN1) Antibody
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E3 ubiquitin-protein ligase synoviolin (SYVN1) Antibody
20-abx211798
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E3 Ubiquitin-Protein Ligase Synoviolin (SYVN1) Antibody
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E3 Ubiquitin-Protein Ligase Synoviolin (SYVN1) Antibody
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E3 Ubiquitin-Protein Ligase Synoviolin (SYVN1) Antibody
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E3 Ubiquitin-Protein Ligase Synoviolin (SYVN1) Antibody
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E3 Ubiquitin-Protein Ligase Synoviolin (SYVN1) Antibody
20-abx002034
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E3 Ubiquitin-Protein Ligase Synoviolin (SYVN1) Antibody
20-abx302155
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
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  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
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E3 Ubiquitin-Protein Ligase Synoviolin (SYVN1) Antibody (HRP)
20-abx314566
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
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Mouse E3 ubiquitin-protein ligase synoviolin (SYVN1) ELISA Kit
abx390695-96tests 96 tests
EUR 1093.2

Syvn1 ELISA Kit| Mouse E3 ubiquitin-protein ligase synoviolin E
EF016338 96 Tests
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E3 Ubiquitin-Protein Ligase Synoviolin (SYVN1) Antibody (FITC)
20-abx314567
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
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ELISA kit for Mouse E3 ubiquitin-protein ligase synoviolin (SYVN1)
KTE70316-48T 48T
EUR 398.4
Description: Quantitative sandwich ELISA for measuring Mouse E3 ubiquitin-protein ligase synoviolin (SYVN1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse E3 ubiquitin-protein ligase synoviolin (SYVN1)
KTE70316-5platesof96wells 5 plates of 96 wells
EUR 2538
Description: Quantitative sandwich ELISA for measuring Mouse E3 ubiquitin-protein ligase synoviolin (SYVN1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse E3 ubiquitin-protein ligase synoviolin (SYVN1)
KTE70316-96T 96T
EUR 646.8
Description: Quantitative sandwich ELISA for measuring Mouse E3 ubiquitin-protein ligase synoviolin (SYVN1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

E3 Ubiquitin-Protein Ligase Synoviolin (SYVN1) Antibody (Biotin)
20-abx314568
  • EUR 493.20
  • EUR 2214.00
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  • EUR 360.00
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Nori® Human IL-12 ELISA Kit- Synovial Fluid
GR106141-SF 96-well
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CryoProtX
M-MD1-61 46 x 1.5 ml ml
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Nori® Human VEGF ELISA Kit- Synovial Fluid-2 Plates
GR111005-SF-2 2 x 96-well
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Human Bone Joint PrimaCell: Normal Synovial Cell
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Nori® Human IL-13 ELISA Kit- Synovial Fluid-2 Plates
GR111006-SF-2 2 x 96-well
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CryoProtX Eco Screen
M-MD1-61-ECO 46 x 1.5 ml ml
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Description: CryoProtX Eco Screen

Human Synovial Microvascular Endothelial Cells
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CryoProtX Mix Reagents 1.5 mL
M-MDSR-61 1.5 ml ml
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Description: CryoProtX Mix Reagents 1.5 mL

CryoProtX Mix Eco Reagents 1.5 mL
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Description: CryoProtX Mix Eco Reagents 1.5 mL

Paraffin Tissue Section - Human Bone Tumor: Synovial Sarcoma
T2235023-8 5 slides
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Human Bone Joint PrimaCell: Normal Synovial Cells Growth Medium
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Human Bone Joint Tissue Preparation Buffer: Normal Synovial Cells
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SSX1 Synovial Sarcoma, X Breakpoint 1 Human Recombinant Protein
PROTQ16384 Regular: 10ug
EUR 380.4
Description: SSX1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 211 amino acids (1-188 a.a) and having a molecular mass of 24.3kDa.;SSX1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

SSX2 Synovial Sarcoma, X Breakpoint 2 Human Recombinant Protein
PROTQ16385 Regular: 10ug
EUR 380.4
Description: SSX2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 210 amino acids (1-188a.a) and having a molecular mass of 24.0kDa. ;SSX2 is fused to a 22 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

FD Tissue Cryoprotection Solution™
PC102 250 ml
EUR 156

20 x Synovial Fluid Solution
GR103059 100 mL
EUR 70

Mycoplasma synoviae PCR kit
PCR-M405-48D 50T
EUR 543.6

Mycoplasma synoviae PCR kit
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Human Bone Joint PrimaCell: Normal Synovial Cells Growth Supplements with Serum (for 500 ml medium)
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Synovial sarcoma tissue array
SS1001 each
EUR 348
Description: Synovial sarcoma tissue array, including TNM, clinical stage and pathology grade, 50 cases/100 cores

Mycoplasma synoviae One-Step PCR kit
Oneq-M405-100D 100T
EUR 1039.2

Mycoplasma synoviae One-Step PCR kit
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Nori® Canine (dog) IL-6 ELISA Kit- Synovial Fluid
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EUR 461

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EUR 461

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Synovial Sarcoma, X Breakpoint 1 Protein
20-abx262587
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EUR 461

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EUR 461

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNC942051-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), CF594 conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNC942051-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), CF594 conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNC942062-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), CF594 conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNC942062-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), CF594 conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNC942085-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF594 conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNC942085-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF594 conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNC802051-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), CF680 conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNC802051-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), CF680 conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNC802062-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), CF680 conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNC802062-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), CF680 conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNC802085-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF680 conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNC802085-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF680 conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNC702051-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), CF770 conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNC702051-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), CF770 conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNC702062-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), CF770 conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNC702062-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), CF770 conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNC702085-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF770 conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNC702085-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF770 conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNC882051-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), CF488A conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNC882051-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), CF488A conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNC882062-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), CF488A conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNC882062-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), CF488A conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNC882085-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF488A conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNC882085-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF488A conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNC812051-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), CF680R conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNC812051-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), CF680R conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNC812062-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), CF680R conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNC812062-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), CF680R conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNC812085-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF680R conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNC812085-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF680R conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNC052051-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), CF405M conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNC052051-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), CF405M conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNC052062-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), CF405M conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNC052062-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), CF405M conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNC052085-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF405M conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNC052085-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF405M conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNC042051-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), CF405S conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNC042051-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), CF405S conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNC042062-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), CF405S conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNC042062-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), CF405S conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNC042085-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF405S conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNC042085-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF405S conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNC402051-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), CF640R conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNC402051-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), CF640R conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNC402062-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), CF640R conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNC402062-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), CF640R conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNC402085-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF640R conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNC402085-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF640R conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNCAP2051-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNCAP2051-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNCAP2062-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNCAP2062-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNCAP2085-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNCAP2085-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNCA2051-250 250uL
EUR 472.8
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), APC conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNCA2062-250 250uL
EUR 472.8
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), APC conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNCA2085-250 250uL
EUR 472.8
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), APC conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNCP2051-250 250uL
EUR 472.8
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), PerCP conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNCP2062-250 250uL
EUR 472.8
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), PerCP conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNCP2085-250 250uL
EUR 472.8
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), PerCP conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNCR2051-250 250uL
EUR 472.8
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), RPE conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNCR2062-250 250uL
EUR 472.8
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), RPE conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNCR2085-250 250uL
EUR 472.8
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), RPE conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNCH2051-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNCH2051-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNCH2062-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNCH2062-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNCH2085-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNCH2085-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNCB2051-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), Biotin conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNCB2051-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), Biotin conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNCB2062-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), Biotin conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNCB2062-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), Biotin conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNCB2085-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), Biotin conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNCB2085-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), Biotin conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNUB2051-100 100uL
EUR 316.8
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), Concentration: 0.2mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNUB2051-50 50uL
EUR 486
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), 1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNUB2051-500 500uL
EUR 615.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), Concentration: 0.2mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNUB2062-100 100uL
EUR 316.8
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), Concentration: 0.2mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNUB2062-50 50uL
EUR 486
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), 1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNUB2062-500 500uL
EUR 615.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), Concentration: 0.2mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNUB2085-100 100uL
EUR 316.8
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), Concentration: 0.2mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNUB2085-50 50uL
EUR 486
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), 1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNUB2085-500 500uL
EUR 615.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), Concentration: 0.2mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNC472051-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), CF647 conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNC472051-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), CF647 conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNC472062-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), CF647 conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNC472062-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), CF647 conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNC472085-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF647 conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNC472085-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF647 conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNC552062-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), CF555 conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2062) Antibody
BNC552062-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2062), CF555 conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNC552085-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF555 conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2085) Antibody
BNC552085-500 500uL
EUR 654
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF555 conjugate, Concentration: 0.1mg/mL

TLE1 (Synovial Sarcoma Marker) (TLE1/2051) Antibody
BNC612051-100 100uL
EUR 279.6
Description: Primary antibody against TLE1 (Synovial Sarcoma Marker) (TLE1/2051), CF660R conjugate, Concentration: 0.1mg/mL


Since this article has been alleged infringement and corresponding study author did not respond to our request to prove the authenticity of the data and figures, “Mir-20a Regulates fibroblast-like synoviocyte proliferation and apoptosis in rheumatoid arthritis, by X.-J. Wei, X.- W. Li, J.-L. Lu, long Z.-X., J.-Q. Liang, S.-B. Wei, C.-X. Lu, Lu W.-Z., published in Eur Rev Med Pharmacol Sci 2017; 21 (17): 3886-3893-PMID: 28,975,975 “has been withdrawn. Publisher apologizes for any inconvenience this may cause.